This study aims to explore the question, “When the FED speaks, do international financial markets respond?” through an extended analysis using a two-step regression method. Initially, we perform a regression analysis on the tone of speeches by FED Chairpersons, based in the US, against the rate of return on major stock exchanges from over 60 countries. Subsequently, to account for the variability of these coefficients in the initial phase, we incorporate macroeconomic and financial indicators, such as proximity, GDP per capita, and lending interest rates, into our analysis to test our hypotheses. Our findings indicate that proximity negatively influences return changes, and other factors, including total reserves, lending interest rates, external debt of stock, and exchange rates, show a predictive capacity for these variations from the first estimate.